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Australian Prescriber Vol. 27 No. 5 2004

Diabetes and antipsychotic drugs

People with schizophrenia have an increased chance of developing diabetes. The risk of diabetes can also be increased by some of the medicines used to treat schizophrenia.

Patients with diabetes and schizophrenia need to have their blood tested to make sure it does not contain too much sugar. They can put on weight so they usually have to follow a weight reduction diet and increase physical activity. This may be difficult, but can help to prevent heart disease. It is important not to stop taking the medicines, despite the risk of diabetes, as schizophrenia is likely to get worse if treatment is stopped.