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Australian Prescriber Vol. 32 No. 2 2009

Botulinum toxin

Botulinum toxin can harm as well as heal. It is poisonous when consumed in contaminated food. However, when injected in very small doses it has medicinal properties and works by weakening overactive muscles.

This medicine is used to bring some relief for spasticity, particularly in children with cerebral palsy and in adults after stroke. It is also used to treat eyelid tics, facial muscle spasms and excessive sweating.

Botulinum toxin is well known for its cosmetic uses, namely to reduce facial wrinkles such as frown lines and crow's feet.

As the effects of botulinum toxin are only temporary, repeat injections are usually needed after 3−4 months. This medicine can cause side effects. These may be mild such as tenderness or bruising at the injection site. However, difficulty with swallowing and speaking may be signs of something more serious and need immediate medical attention.