Summary

Recently updated Australian guidelines recommend that advice on smoking, nutrition, alcohol use, physical activity and body weight should be part of routine management of hypertension for all patients, regardless of drug therapy. Smoking cessation is recommended to reduce overall cardiovascular risk. Healthy eating, reducing dietary sodium and alcohol intake, regular physical activity and achieving a healthy body weight are all effective in lowering blood pressure.

 

Introduction

Hypertension is a major risk factor for stroke and coronary heart disease, and is a major contributor to the onset and progression of chronic heart failure and chronic kidney failure. Guidelines by the National Heart Foundation of Australia1recommend that doctors caring for patients with hypertension should routinely provide advice on smoking, nutrition, alcohol use, physical activity and body weight.

Lifestyle modification is indicated for all patients with hypertension, regardless of drug therapy, because it may reduce or even abolish the need for antihypertensive drugs. In addition to the immediate goal of lowering blood pressure, the recommended lifestyle changes confer a range of health benefits, including better outcomes of common chronic diseases. Effective approaches to promoting lifestyle changes in primary care are listed in Box 1.

Box 1

Lifestyle recommendations for lowering blood pressure

Smoking

Give all patients clear, unambiguous advice to stop smoking. Assess for nicotine dependence (e.g. time of last cigarette, withdrawal symptoms) and offer counselling, support services and pharmacotherapy as appropriate.

Nutrition

Advise patients to limit salt intake to 4 g/day (65 mmol/day sodium) or less by choosing foods normally processed without salt, foods labelled 'no added salt' or 'low salt' (or 'reduced salt' products when other options are unavailable). High-salt processed foods (ham, bacon, sausages, canned or packet soups, stock cubes), salty snacks, takeaway foods high in salt, or salt added during cooking or at the table should be avoided.

Advise patients to eat a diet that includes mainly plant-based foods (e.g. fruits, vegetables, pulses and a wide selection of wholegrain foods, moderate amounts of low-fat or reduced-fat dairy products), moderate amounts of lean unprocessed meats, poultry and fish, moderate amounts of polyunsaturated and monounsaturated fats (e.g. olive oil, canola oil, reduced-salt margarines).

Patients with hypertension who are not taking potassium-sparing diuretics and have

normal renal function can be advised to increase potassium intake by eating a wide variety of fruits and vegetables, plain unsalted nuts (limit quantity and frequency to avoid excess kilojoules), and legumes (e.g. beans, lentils, dried peas).

Alcohol

Advise patients to limit alcohol intake to a maximum of two standard drinks per day (men) or one standard drink per day (women) and have at least two alcohol-free days per week.

Physical activity

Advise patients to become physically active. Aim for 30 minutes of moderate intensity* physical activity on most, if not all, days of the week.1 The daily dose can be accumulated in shorter bouts (e.g. three 10-minute walks). Advise against isometric exercise routines that may raise blood pressure (e.g. weightlifting), except within professionally supervised programs.

Body weight

Advise patients with hypertension how to achieve and maintain a healthy body weight target**: waist circumference less than 94 cm (men) or less than 80 cm (women) and body mass index (BMI) less than 25 kg/m2.

* 'Moderate' means any activity sufficiently intense to cause a slight increase in breathing and heart rate, and may cause light sweating (e.g. brisk walking, lawn mowing, low-paced swimming, cycling, gentle aerobics).

** Targets are based on data from European populations and may not be appropriate for all ages and ethnocultural groups. Compared with Europeans, the BMI cut-point associated with increased risk of type 2 diabetes and cardiovascular disease is typically higher for Polynesian populations and lower for Aboriginal and Torres Strait Islander populations and some Asian populations.

 

Smoking

Smoking is a strong independent risk factor for cardiovascular disease. Quitting is acknowledged to be one of the most effective lifestyle interventions for preventing cardiovascular disease and premature deaths.

Smoking causes an immediate increase in blood pressure and heart rate that persists for more than 15 minutes after one cigarette. People who smoke show higher ambulatory blood pressure levels than non-smokers.2

Elevated blood pressure and smoking are the two most important risk factors for subarachnoid haemorrhage in the Asia-Pacific region. The risk of myocardial infarction is 2-6 times higher and the risk of stroke is three times higher in people who smoke, compared with non-smokers.1

Smoking cessation markedly reduces overall cardiovascular risk, including the risk of coronary heart disease and stroke, compared with continued smoking. In patients with coronary heart disease, smoking cessation is associated with a 36% reduction in the risk of all-cause mortality.3Although smoking is known to increase the risk of developing hypertension, there is currently no evidence that smoking cessation directly reduces blood pressure in people with hypertension.2

 

Nutrition

Determining the influence of various nutrients on blood pressure and cardiovascular risk is a complex and evolving research area. While some relationships between food and cardiovascular health have not yet been clearly quantified, there is sufficient evidence to recommend that people with hypertension should avoid salty foods and aim for a healthy eating pattern.

Restricting salt intake

High dietary sodium intake is associated with an increased incidence of stroke, and with increased risk of death due to coronary heart disease or cardiovascular disease.4Reducing dietary sodium by approximately 1700 mg (75 mmol) per day can lower systolic blood pressure by 4-5 mmHg in hypertensive individuals and 2 mmHg in normotensive individuals.4,5This may reduce the need for antihypertensive drugs. Responses vary between individuals and are generally greatest among the elderly and those with severe hypertension.

There is weak evidence suggesting that weight loss combined with reduced dietary sodium may be more effective at lowering blood pressure than salt avoidance alone.4Reduced-salt diets in combination with thiazide diuretics may predispose elderly patients to hyponatraemia, so electrolytes should be monitored regularly.

Dietary potassium

Some clinical trials suggest that increasing dietary potassium by approximately 2100 mg (54 mmol) per day can reduce systolic blood pressure by 4-8 mmHg in hypertensive individuals and 2 mmHg in normotensive individuals. Potassium-rich whole foods, such as bananas, kiwi fruit, avocado, potatoes (with skin), nuts and yoghurt, are more effective in reducing blood pressure than potassium supplements, which are potentially toxic.4

High potassium intake can produce hyperkalaemia in people with impaired renal function. It should be recommended only for those with known normal renal function.

Healthy eating

Blood pressure reductions in people with and without hypertension can be achieved by a healthy eating pattern based on the Dietary Approach to Stop Hypertension (DASH) diet, in addition to reduced salt intake.4 The DASH diet emphasises fruits, vegetables, whole grains, low-fat dairy products and dietary fibre, while being low in dietary sodium, cholesterol and saturated fat.6

High-dose (at least 3 g/day) omega-3 polyunsaturated fatty acid supplement (fish oil) may also lower blood pressure in hypertensive individuals.2Evidence is insufficient to recommend calcium and magnesium supplements or increasing dietary fibre intake alone (for example, taking supplemental fibre rather than increasing fruit and vegetable intake) to reduce blood pressure.

Alcohol

Evidence for cardiovascular benefits of light drinking has been challenged by a recent meta-analysis.2Regardless of this debate, evidence is emerging that all levels of alcohol intake increase blood pressure. Moderate drinking can increase blood pressure, while binge drinking appears to increase the risk of hypertension.1Epidemiological data show a linear relationship between alcohol consumption and hypertension prevalence.2Reducing alcohol consumption can lower systolic blood pressure by an average of 3.8 mmHg in patients with hypertension.7The Heart Foundation recommends that patients with hypertension limit their alcohol intake to a maximum of two standard drinks per day for men, and one standard drink per day for women.1

 

Physical activity

It is clear that physical activity lowers resting and daytime ambulatory blood pressure.1In clinical trials of people with hypertension, regular aerobic activity reduced systolic blood pressure by an average of 6.9 mmHg and diastolic blood pressure by 4.9 mmHg.8

Regular physical activity has an independent cardioprotective effect.1Regular exercise is associated with an increase in high-density lipoprotein cholesterol and with reductions in body weight, waist circumference, percentage body fat, insulin resistance, systemic vascular resistance, plasma noradrenaline and plasma renin activity.8

 

Body weight

There is a direct association between blood pressure and body weight and/or abdominal adiposity. Weight loss studies show that clinically significant blood pressure reductions can be achieved by modest weight loss in people with and without hypertension and that blood pressure reduction is proportional to weight loss.2Every 1% reduction in body weight lowers systolic blood pressure by an average of 1 mmHg.1Losing 4.5 kg reduces blood pressure or prevents hypertension in a large proportion of overweight people, while losing 10 kg can reduce systolic blood pressure by 6-10 mmHg.1 In overweight patients with hypertension, weight-reducing diets can achieve a 3-9% decrease in body weight and may reduce systolic and diastolic blood pressure by approximately 3 mmHg.

Weight reduction confers a range of other cardiovascular health benefits including reduced insulin resistance and hyperlipidaemia, and reduced risk of left ventricular hypertrophy and obstructive sleep apnoea.2

 

Integrating lifestyle advice into clinical management

Practical resources are now widely available to help Australian health professionals effectively promote positive lifestyle changes (see Box 2). These encourage and support health professionals to take a systematic approach, by providing a simple framework for broaching the subject with patients, negotiating goals, giving tailored advice including written information, and referring patients to more information and other medical and support services.

The '5As' approach − Ask, Assess, Advise, Assist and Arrange − is often advocated as a useful framework for primary care health professionals to provide brief interventions for lifestyle modification in the clinical setting.


Box 2 Resources for promoting lifestyle management to patients

    • Heart Foundation's Heart Health Information Service - for professional and consumer resources phone 1300 36 27 87.
    • Life scripts (including resources developed for Aboriginal and Torres Strait Islander people and pregnant women)http://www.agpn.com.au
    • Litt J, editor. The 'Green Book'. Putting prevention into practice. 2nd ed. South Melbourne: Royal Australian College of General Practitioners; 2006.
    • Harris M, Bailey L, Bridges-Webb C, Furler J, Joyner B, Litt J, et al. The 'Red Book'. Guidelines for preventive activities in general practice. 6th ed. South Melbourne: Royal Australian College of General Practitioners; 2005.
    • Egger G, Binns A, Rossner S. Lifestyle medicine. Sydney: McGraw-Hill; 2007.
    • National Aboriginal Community Controlled Health Organisation. National guide to a preventive health assessment in Aboriginal and Torres Strait Islander peoples. South Melbourne: Royal Australian College of General Practitioners; 2005.
    • Lifestyle changes (special issue). Aust Fam Physician 2008; 37:1-96.
    • Shand F, Gates J. Treating alcohol problems: guidelines for general practitioners. National Alcohol Strategy. Canberra: Australian Government Department of Health and Ageing; 2004.
    • National Health and Medical Research Council. Clinical practice guidelines for the management of overweight and obesity in adults. Canberra: NHMRC; 2003.
    • Zwar N, Richmond R, Borland R, Stillman S, Cunningham M, Litt J. Smoking cessation guidelines for Australian general practice. Practice handbook. Canberra: Australian Government Department of Health and Ageing; 2004.
    • Quit resources: http://www.quit.org.au
     

    Conclusion

    Current Australian guidelines for the management of hypertension recommend lifestyle modification as an important and effective first-line treatment strategy. In addition to the significant lowering of blood pressure achieved through changes to eating patterns, moderating alcohol intake, weight loss and regular physical activity, lifestyle measures (including smoking cessation) confer other significant cardiovascular health benefits. Regardless of other treatments indicated, all patients who need to lower their blood pressure should be given advice and support to achieve and maintain healthy behaviours.

     

    Self-test questions

    The following statements are either true or false.

    1. There is evidence that smoking cessation reduces blood pressure in people with established hypertension.
    2. A low potassium diet may help to reduce blood pressure in patients with hypertension.

    Answers to self-help questions

    1. False
    2. False
     

    References

    1. National Heart Foundation of Australia. Guide to management of hypertension 2008. Assessing and managing raised blood pressure in adults. NHF; 2008. http://www.heartfoundation.org.au/Professional_Information/Clinical_Practice/Hypertension.htm [cited 2008 Nov 10]
    2. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, et al. 2007 Guidelines for the Management of Arterial Hypertension. The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 2007;25:1105-87.
    3. Critchley J, Capewell S. Smoking cessation for the secondary prevention of coronary heart disease. Cochrane Database Syst Rev 2004:CD003041.
    4. National Heart Foundation of Australia. Summary of evidence statement on the relationships between dietary electrolytes and cardiovascular disease. October 2006. http://www.heartfoundation.org.au/document/NHF/NHFA_DietaryElectrolytes_CVD_SummaryofEvidenceSt_2006_FINAL.pdf[cited 2008 Nov 10]
    5. He FJ, MacGregor GA. Effect of longer-term modest salt reduction on blood pressure. Cochrane Database Syst Rev 2004:CD004937.
    6. Khan NA, Hemmelgarn B, Padwal R, Larochelle P, Mahon JL, Lewanczuk RZ, et al. The 2007 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy. Can J Cardiol 2007;23:539-50.
    7. Dickinson HO, Mason JM, Nicolson DJ, Campbell F, Beyer FR, Cook JV, et al. Lifestyle interventions to reduce raised blood pressure: a systematic review of randomized controlled trials. J Hypertens 2006;24:215-33.
    8. Fagard RH, Cornelissen VA. Effect of exercise on blood pressure control in hypertensive patients. Eur J Cardiovasc Prev Rehabil 2007;14:12-7.

    Nancy Huang

    National Manager - Clinical Programs, National Heart Foundation of Australia, Melbourne; Karen Duggan, Director, Hypertension Service, South Western Sydney Area Health Service

    Karen Duggan

    Director, Hypertension Service, South Western Sydney Area Health Service, and Chair, National Blood Pressure and Vascular Disease Advisory Committee; and Jenni Harman, Medical Writer, Meducation, Sydney